A STRUCTURAL APPROACH TO DISCOVERY

Xtal BioStructures specializes in X-ray crystallography and biophysical characterization, offering structural biology insights through contract research services.

PROTEIN PRODUCTION AND PURIFICATION 

XTAL produces high quality proteins, custom designed to meet the needs of our clients in X-ray crystallography, biophysical characterization, screening, and assay development applications.
BIOPHYSICAL CHARACTERIZATION

XTAL offers characterization of protein:ligand interactions via SPR, ITC, and TSA (DSF). Applications include characterization of ligand binding kinetics, fragment-based screening, optimization of protein storage conditions, and pre-formulation. 
X-RAY CRYSTALLOGRAPHY

XTAL offers high resolution protein structure determination, including small molecule or antibody complexes and novel structures, with data from synchrotron sources.
EPIGENETICS & BROMODOMAINS 

XTAL produces higher order nucleosome core particle complexes and a broad array of bromodomain proteins.
OTHER SERVICES

XTAL offers a broad array of scientific expertise, implementing various programs such as assay development and mechanism of action studies.