A STRUCTURAL APPROACH TO DISCOVERY
BIOPHYSICAL CHARACTERIZATION X-RAY CRYSTALLOGRAPHY EPIGENETIC and BROMODOMAIN PROTEINS OTHER SERVICES
XTAL produces high quality proteins, custom designed to meet the needs of our clients in X-ray crystallography, biophysical characterization, screening, and assay development applications.
XTAL offers characterization of protein:ligand interactions via SPR, ITC, and TSA (DSF). Applications include characterization of ligand binding kinetics, fragment-based screening, optimization of protein storage conditions, and pre-formulation.
XTAL offers high resolution protein structure determination of proteins, protein/small molecule/antibody complexes, and novel structures with data from synchrotron X-ray sources.
XTAL produces higher order nucleosome core particle complexes and a broad array of bromodomain proteins.
XTAL offers a broad array of scientific expertise, implementing various programs such as assay development and mechanism of action studies.
EPIGENETIC and BROMODOMAIN PROTEINS